Adapted from the popular term YOLO (You Only Live Once)....what you really mean is YOYO (You are Only Young Once) so live it up to the fullest!
Your friend asks want to take one more shot,, and you respond no I'm too drunk, and he replies YOYO!!! and we take 2 more shots because we are only young once!
by Maggie Abreggo August 27, 2012
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Acronym for: You're only young once.

Do things while you are young and can still get away with them. Don't settle down until after your millionth drink/smoke.
Wanna go out?
We work tomorrow at 9am.
What are you, 70? Let's go!
Alright, YOYO!
by Blue Rose 2012 July 20, 2012
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Medical slang, but can be used anywhere: Means: You're on your own. Used in a hospital on the day of discharge as in the phrase "OOB,OTD, YOYO" : Out of Bed, Out the Door, You're on your own. Can be used by parents of colleged aged kids, or by someone breaking up with someone else. .
I've had it with you, YOYO!
by DoctorSteve September 13, 2006
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Stands for: Your only young once.
Tom: Hey I bet you won't chug that whole bottle.
Ben: ah idk...
Tom: yoyo bro
Ben: glug* glug* glug*
by Alex (the man) Rosentreter October 3, 2008
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When you need a poo really badly so you yoyo it in and out of your bumhole
Damn man ive been yoyoing for about an hour, can i use the toilet yet m8
by madmuff January 10, 2017
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A totally amazing man with an uncanny skill at fencing, and unmistakably smooth with the ladies. If you know someone named yoyo then "Hide yo wife, Hide yo kids" .....
by yobopobo May 28, 2014
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Yo-Yo: A term used to describe the sponging 10 - 14 year olds who roam around amusement arcades, accosting strangers for money. This is usually opened with the statement "Yo, yo, gimme fifty pee."
Yo-Yo's are usually sent packing with a little verbal assault (or physical assault - it's all good in this situation).
"Ah hell, Yo-Yo's at ten o'clock high."

"Yo-Yos. Just ignore 'em."
by Mondo Kane September 24, 2004
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