1 definition by WhtRhino

baffle

To completely dumbfound, confuse, or otherwise render speechless by either asking a question or stating something beyond their intelligence.

Toni:The mechanism of endocannabinoid synaptic transmission is believed to occur as follows: first, transmission of the excitatory neurotransmitter glutamate causes an influx of calcium ions into the post-synaptic neuron.

Guy: ummm... what? (Toni baffled Guy)

by WhtRhino October 7, 2008