CognitiveFuel's definitions
Benzyl chloride (BnCl) is a molecule that is a used to make pharmaceuticals and can also be used to make Phenyl-2-Propanone. Benzyl chloride is synthesized from toluene (benzyl hydride) by chlorination with TCCA (trichloroisocyanuric acid, pool chlorine) in sunlight with lithium bromide as a catalyst. The lithium bromide makes it so that you get benzyl chloride in hours instead of days. Phenyl-2-Propanone is synthesized by adding benzyl chloride in diethyl ether (or even better, dibutyl ether for higher yield) and adding magnesium turnings. You make benzyl magnesium chloride. Then you react it with acetonitrile and then do a hydrochloric acid work-up to get Phenyl-2-Propanone.
Properties
Chemical formula
C7H7Cl
Molar mass
126.58 g·mol−1
Appearance
Colorless to slightly yellow, toxic liquid
Odor
Pungent, aromatic
Density
1.100 g/cm3
Melting point
−39 °C (−38 °F; 234 K)
Boiling point
179 °C (354 °F; 452 K)
Solubility in water
very slightly soluble (0.05% at 20 °C)
Solubility
soluble in ethanol, diethyl ether, chloroform, CCl4
miscible in organic solvents
Vapor pressure
1 mmHg (20 °C)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Poisonous and carcinogenic; lachrymator
Properties
Chemical formula
C7H7Cl
Molar mass
126.58 g·mol−1
Appearance
Colorless to slightly yellow, toxic liquid
Odor
Pungent, aromatic
Density
1.100 g/cm3
Melting point
−39 °C (−38 °F; 234 K)
Boiling point
179 °C (354 °F; 452 K)
Solubility in water
very slightly soluble (0.05% at 20 °C)
Solubility
soluble in ethanol, diethyl ether, chloroform, CCl4
miscible in organic solvents
Vapor pressure
1 mmHg (20 °C)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Poisonous and carcinogenic; lachrymator
I reacted toluene (benzyl hydride, paint thinner) with TCCA (trichloroisocyanuric acid, pool chlorine) in sunlight with lithium bromide catalyst and got benzyl chloride in a matter of hours.
by CognitiveFuel November 28, 2022
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by CognitiveFuel March 11, 2023
Get the Vitamin E2 mug.3,4-MethyleneDioxyPhenyl-2-Propanone (MDP2P) is a yellow chemical that has a melting point of 87-88 °C and a Boiling point range of 115-170 °C at around 30 mmhg. MDP2P can be synthesized by oxidation of MDP2Pol (3,4-MethyleneDioxyPhenyl-2-Propanol) using either sodium chlorite or sodium hypochlorite in hydrochloric acid and a byproduct is chlorine gas (if hydrochloric acid isn't used, then you will get the haloform reaction). MDP2P can also be synthesized by a grignard reaction of 3,4-MethyleneDioxyBenzyl magnesium chloride (formed from 3,4-Methylenedioxybenzyl chloride and magnesium turnings in diethyl ether) and acetonitrile followed by hydrochloric acid work-up. MDP2P can also be synthesized from wacker oxidation of safrole. Reaction of MDP2P with an ethanol solution of ethylamine and Aluminum Galinstan amalgam reduces the MDP2P-ethylimine intermediate into MDEA. 3,4-MethyleneDioxyPhenyl-2-Propanone is a yellow oily ketone. It is yellow green in the sunlight. MDP2P can also be synthesized by reacting sesamyl tosylate (SmOTs,3,4-Methylenedioxyphenyl tosylate) with ethyl acetoacetate and sodium ethoxide and Copper iodide catalyst and heat. 3,4-MethyleneDioxyPhenyl-2-Propanone is also called Sesamyl-2-Propanone (Se2P, Ses2P, Sm2P), Sesamylacetone, and Piperonyl Methyl Ketone.
I synthesized 3,4-MethyleneDioxyPhenyl-2-Propanone (MDP2P) by reacting 3,4-MethyleneDioxyBenzyl magnesium chloride and acetonitrile followed by hydrochloric acid work-up.
by CognitiveFuel October 29, 2022
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