a term used to describe your most chilling of all your boys. Your "guyzer" is only used to describe a select few of your friends that you truely trust, appreciate, back, and want to associate youself with.
"I said yooo guyzer, what are you saying tonight? You wanna chill down at the spot?"

"How are you guyzer, your looking good today ;)"
by Katzilla January 17, 2006
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A truly nice guy with no bad intentions. Things may not always go as Guyzer plans, but with everything Guyzer does, he means well.

Comedy is a big part of Guyzer. He always tries to make people smile and laugh even when things aren’t going well, even if those things are his own misdoings.

It’s always nice to have a Guyzer around.
A Guyzer is a truly nice guy with no bad intentions.
by John Becks January 16, 2022
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