1 definition by themanwithnopseudonym
Injecting heroin and cocaine in the same shot. Intensifies the heroin "flash" or rush of euphoria. For the first 30 second you feel like Tony Montana tit fucking Ashley Pridgen, followed by hours of opiate comfort.
"I just did a speedball a little while ago. Man, lemme tell ya, it felt like titty fucking an angel"
by themanwithnopseudonym September 5, 2011