by Josh January 2, 2005
A character from the T.V show "South Park". He has very messy blonde hair and supposedly sufferes from A.D.D but his twitching and nervous personality is due to the large amounts of caffeine he consumes. In Series 6, Tweek became the main characters replacement for Kenny, alongside Butters, after he "permeanantly" died at the end of the previous series.
by Issy Aidsfunop January 15, 2006
to be overly excited at a situation or event that is highly positive and causes exuberance beyond classification of excitement.
Scott won a vacation to Hawaii, a place he always wanted to go, causing him to call his friends and tweek.
by BT14 July 30, 2007
When a person who calls himself a business manager, steals people’s money, is paranoid from 15,000 dollars of crack in a burnt stem.
by Jaythereal December 22, 2022
Tweeking: A combination of two words, two and week. When you have been on meth (cranking in the old days) and up for two weeks you have a tendency to talk funny and slur your words. After two weeks when you try to tell someone what your problem is all you can say is "I tweek..." After coming down for a day before your next trip you realize that you said tweek and also realize that it is not only a homonym with tweak, which means to bend or force out of shape, but it can also be synonymous. And since you were very bent you think it is funny and go get an eightball, and your again tweeking in no time at all. This is the origin of the word, believe me I was there.
Moral of the Story: Don't do drugs
Moral of the Story: Don't do drugs
Pleeezzzze hlp ma, I tweeeeeeek blaaargghhh *thump*
In the next day or two after your regain consciousness you say; "Man I was tweeking."
In the next day or two after your regain consciousness you say; "Man I was tweeking."
by cawper January 9, 2008
Tweeking is any change to a product or document that you think will take two hours but ends up taking two weeks. Tw(o)-(w)eeks.
by BigMickSydney April 26, 2009