i believe that winnie the pooh was the first to use an expression like this. a young snoop doggy dogg heard this and immediately bastardized it to fit his situations.
"hephalumps and woozles" changed to "fo' shizzle my nizzle"
by the lazy bhikkhu March 14, 2003
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As we All know fo' shizzle my nizzle used To be a common phrase said by Many cooks Meaning Oh Shit I burned my nose!
Cook 1 : that melted Cabbage smells good!

Cook 2 : Yea it does!
Cook 1 : (leans down to sniff and Grease hits his nose )
Cook 1 : FO SHIZZLE MY NIZZLE!!!
by Jonathon21 August 7, 2005
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fo' shizzle my nizzle was origianally pattented by Martha Stewart, a white woman, and not a black man. While basking in the wonderfully spagetti she had just had, which contained home-grown mushrooms, she happened to decide to work in the garden. She needed her "shizzle" or aka "shovel" to work with her "nizzle" aka "nutmeg".
Martha: Fo' shizzle my nizzle. (i need the shovel for my nutmeg)
by Marion June 2, 2003
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It means that we gonna keep it crack-a-lackin.
Homie#1 "Yo, dogg, let's score some wizzle and smoke us a jizzle."
Homie#2 "Fo' shizzle my nizzle."
Homie#1 "Chuch."
by Doggy Fizzle May 10, 2003
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yo, let me bust this flow now, huh damn this ganga got me like wow, so while i toke, ill lay down a definition, skip a choke, ill pack the heat, make the this site sizzle, so listen up learn from a this dizzle, shit u think all i know is using them words- bizzle rizzle mizzle, fuck, i help snoop sharpen his rhymes with my lyrical chisel, my shit wont fizzle, damn right i keep the game tight, i got these lines from time to time, give it wut i got, blow ur mind, all i need is a sac with a dime, pull out a j, and just smoke away, u know how i rep, cuz i chill in the city by the bay all day everyday, sf repping, aint got no haters steppin, down here in cali we roll big with the thc, westcoast forever its the mothafucking way to be, so yo i best be out the do' holla back less you be whack cuz u know i can spit at ur game, just dont be tame, im not playin, bring on the rain avoid the light drizzle, holla, fo' shizzle my nizzle
by mynizzle April 25, 2003
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While I concur with the Gap Band's origination of this particularity of the phrase...
Its came to be in more modern times via the "skilliage fo'realiage" of Hip-Hop icon E40 whom originaly dictated the root of Fo'Sheezy, which then evolved as it went to south to LA into "Fo'Shizzle"... indeed history is written "via ferus victorus". However it is always evolving to newer heights.
"fo' shizzle my nizzle" is now "Ph'zz'zz'm'z'lel'le"

But of course my dear comrade!
by SPACEKID September 29, 2005
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