Taking large amounts of cocaine on the regular. Very common in Southern Florida, the rehab capital of the US, which is how the name came about. Snorting cocaine is as common as the flu.
Sally - She looks really strung out from the weekend
Bob - Yeah, she has that South Florida Flu
by cg3851 August 17, 2015
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The University of South Florida (USF) is quite unique. While it prides itself for its exceptional academic programs and medical research facilities, it also is notorious for accepting just about every 18 year old in the state of Florida who got below 1000 on their SATs. Somehow, these students manage to graduate though, even with the distractions of nearby white sand beaches, Gasparilla (an event that takes up the month of Febuary which can be summed up by public intoxication and the performance of sexual favors), and Ybor city (a strip of clubs that the USF students control). USF has a growing football program with the Bull as the mascot. Although the football players are dedicated and got to attend there first bowl game, half of the football players must hold jobs during off season to pay child support.
Nothing compares, The University of South Florida is founded upon the principles of educating geniuses and retards in one classroom. Throw in a few Mardi Gras beads, mass quantities of alcohol, and a bikini and you have the perfect picture of USF.
by Robin A. January 30, 2006
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A third tier institution in Tampax, Florida known for their ridiculously lax admissions standards. They are the third largest "university" in the state of Florida behind UF and UCF. They recently experienced their best football season ever but even that won't attract quality students, as they rank last in the state in number of Merit Scholars. They pride themselves on being the only commuter school in the country with a ranked football team. Recently, administrators at the school announced they would not be able to construct housing for students because of the strong community support for the existing pawn shops and liquor stores that surround the campus. The current money mismanagement crisis at the school has caused students to question the number of luxurious pieces of furniture in the president's office, which include a miniature model of an on-campus football stadium with a plaque reading "Someday..." attached.
Ray Ray: "Dude! Did you get into the Tulsa Welding School?"
Tay Tay: "Nah man. They too selectionative.!"
Ray Ray: "Oh man. That's straight up whack!"
Tay Tay: "It's ok. I just got a football scholarship to the University of South Florida."
by Ray Ray the Jay August 1, 2008
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Mistakenly spraying one's face with bug spray, sunscreen, etc., usually due to not insuring nozzle is pointed away from the face before application
Heidi forgot to check the bugspray nozzle before test spraying and gave herself a South Florida Money Shot
by portlandyakuza August 24, 2019
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The white, fragrant crumbles of moist cheesy like matter tha develop and appear inside a South Florida female's pussy after she walks around outside for very long with labia lips rubbing together in the oppressive humidity and rotting decay of South Florida. For 10 months of the year, t's almost 90% humidity every day.

If you're into that sort of funk, then just break out the Sociable Crackers.

Thanks to the disgusting rotting humid weather herev in Southeast Florida, South Florida Pussy Cheese is available for at least 10 months of the year.

If South Florida Pussy Cheese is not attended to daily, it can quickly turn into A South Florida Black Mold Pussy of Death. If you put that on the Sociable Cracker and eat it, you will die.
That stunning girl over there turns into a disgusting THOT in South Florida after her vagina develops stanky South Florida Pussy Cheese.
by Bosundave121 October 17, 2023
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Chris is a man from south florida who sends in lots of clips of car crashes to the idiots in cars youtube channel
Person 1: Yo you watch idiots in cars
Person 2: Yeah do you like chris from south florida
by UHhUhUHuHuhuhuhUHUHhUH June 8, 2022
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It is when you take you girlfriend on vacation in south florida. the two of you have a nice dinner and you end the night with sex. as you are about to cum you hold her nose and begin to strangle her and right before you cum, you force your dick in her mouth so she is forced to swallow every drop as she gasps for air. (usually white women will let you do this more than once.)
The south florida drowning

man: hey honey, im horny
woman: lets have sex
man: i heard of a new way for oral sex, can we try it?
woman: yeah sure
man: OPEN YOUR MOUTH BITCH!!!!! OH YEAH, OH YEAH, OH YEAH!!!!
woman:GASPS!!!!! AND GASPS!!!
man: im about to cum!!! give me your neck!!!
woman: GASPS, GASPS, GASPS
man: holy shit!!!!! boooom down your throat!!!!
woman: laying lifeless
man: awaiting trial
by Olivetree August 7, 2013
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