Phrase used by an EKG monitor technician, to initiate conversation with a registered cardiac nurse, to inform them of a fatal cardiac dysrhythmia. Usually used for ventricular fibrillation or asystole. Phrase may also be used in reply by the RN to the technician.
Tech: "Oh, Shit!" RN: "What's the matter?" Tech: "The patient in room 3014 is showing asystole on the monitor." RN: "Oh, Shit! That's my second flatline this week!"
by Xanfan October 12, 2009
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A game played on road trips. The passengers in the back seat attempt to squish each other by pretending to react to g-forces when the car travels around a curve. For example, when the car turns right, the players lean left, squishing the passenger on the driver's side.
On our drive to Reno, we played Oh, Shit! so much that CB bruised a rib and lost his hat.
by L January 16, 2005
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Used when something is going Horribly wrong or when in pain (or both)
*Shirt catches Fire* Oh Shit, Oh Shit, Oh Shit, Oh Shit, Oh Shit, Oh Shit, Oh Shit, Oh Shit
by Raffimac March 9, 2016
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an exclaimation to be said with a very loud voice when you realize you have forgotten to do something very important such as:

1) Your Venn English Homework
2) You left your keys locked inside your car
3) You just trip and scrape both of your knees.
Friend "hey man can I have some help with that last question on our english homework?"

You "Oh shit! I left mine at home!"
by J.T. the Bible Scholar February 20, 2004
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Two well-know last words that are said
in an expression of:

1) Impending trouble- When you got a blunt in your hand,
and the po-po appears around the corner;

2) Chargin- When someone finds out a dirty secret
that involves YOU or you're losing in a game;

and/or 3) Catastrophe- at the last second before a
car crash;

EIther way, you are screwed, dude.
Example #1- Dereck had just rolled a fat ass blunt
on the corner when he saw the 5-O rollin' in like
bad weather. "Oh shit!" he thought as he dropped his
last fattie in to the sewer. The cops looked him over,
but Derek didn't get busted for possession.

Example #2- When Henry's mom found his web-blog,
all he could say was, "Ohhhhhhhhhh shit."

Example #3- *SCRRRRREEEEECCCCCHHHHH!!* "OH SHIT!!!"
was the last words that Susan said as her car crashed
into the guy's parked Beamer. If the collision doesn't
nearly kill her, the owner of the car-now-turned-hoopty
will, either with a tire iron or a lawsuit.
by CDSmith1967 March 14, 2006
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1. An expletive expression used when a negative event occurs.

2. An expression used to indicate the state of being impressed.
1. "Oh shit! I just wrecked my dad's Saab after I piss drunk, driving 85 the wrong way down a 25, one-way street. Oh, I may have killed a hooker and a sick poodle, too.

2. "Oh shit! Did you see that African man jump that fence when the police sirens came this way?
by P. Dub July 27, 2006
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