A polite way of saying that you're going to the bath room.
Stands for Be In the "Office".
Guy one: "Hey man I just ate a ton of Mexican food, BIO break."
Guy two: "Dude, nasty..."
by Capt Anarchy May 5, 2009
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Beauty Inside and Out
From Tyra Banks show: beauty comes from inside and out! BIO!
by cng413 May 24, 2010
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BIO , acronym of "Bring It On"
also known as the best warring kingdom in a mmorpg browser game called "Utopia".

GhettoPlayer1: hey man you know BIO?
GhettoPlayer2: OMFG OFC!1 they are teh so l33t they won honor crown on age 34 <3 bio
by Blake Gifford March 9, 2007
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One of the coolest spells to ever grace the Final Fantasy series.
Bio is a poison element spell.
Fire 3:Fire::Blizzard:Ice::Bio:Poison
by Moggle888 August 26, 2003
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BIO is an acronym of the phrase BITCH ITS ON!

it can also be substituted for bring it on but is slightly less effective.
girl1: i bet guys like me more than they like you!

girl2: BIO!
by twentyone31 March 6, 2010
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