In MMO strategy games, the convention that a player will be unprotected by a new alliance he or she joins for the first 48 hours. This allows other players who have had a beef with him to settle things before the new alliance starts defending him.
Alliance Policies: The "48-hour" rule is observed.
by JEH-IT November 11, 2015
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when a couple locks them selves in a room for 48 hours to celebrate getting closer, or after one has been away for a long time, or in preperation for one of them to leave
guy1(military)>hey man when i get home me and my girl are planning on a 48 hour lock up

guy2>dude why the hell would you do that? it sounds borring!

guy1>because ive been in a desert the last 18 months and we want 48 hours to our seves locked up in our rooms
by arcanise September 18, 2009
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When trying to get with a girl and something/someone inturrepts it, one has 48 hours to seal the deal. If failed one spirals deep into the friend zone
john: Hey man my dad walked in on me and stacy last night.
rick: bro you got 48 hours to seal the deal or else its the friend zone for you.
john: ohhh the 48 hour rule (hooking up)
by mileyswag October 31, 2011
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Usually defines a facebook term after unblocking someone. When you want to block the same person again but Facebook doesn't allow you to do so, this best defines 48 hours. Can be also called 2 days.
Han: Dang! I unblocked that guy and now I have to wait for 48 hours!

Lenny: Bonkers, must be a long way to go!
by Ashley Han February 13, 2021
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The rule for the amount of time sperm can stay alive in a person's mouth after oral sex.
Dana: Hi, Katherine, mind if I take a sip of your coke?
Katherine: Are you 48 hour rule safe?
Dana: Yep!
by futureactiveparticiple July 4, 2017
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