CognitiveFuel's definitions

2-chloromethylthiophene

2-Chloromethylthiophene is used as an intermediate to 1-(2-thienyl)-2-Propanone.

In a 2-l. beaker surrounded by an ice-salt bath , and fitted with a mechanical stirrer and a thermometer, are placed 420 g. (392 ml., 5 moles) of thiophene and 200 ml. of concentrated hydrochloric acid. A rapid stream of hydrogen chloride is passed continuously into the mixture with vigorous stirring. When the temperature reaches 0°, 500 ml. of 37% formaldehyde solution is added at a rate that will permit the temperature to remain below 5°. The addition requires about 4 hours. When all the formaldehyde solution has been added, the mixture is extracted with three 500-ml. portions of ether. The ether extracts are combined, washed successively with water and saturated sodium bicarbonate solution, and then dried over anhydrous calcium chloride. The solvent is removed by distillation, and the product is distilled under reduced pressure through a 50-cm. fractionating column. The product boiling at 73–75°/17 mm. is collected. The yield is 257–267 g. (40–41%) of a colorless oily liquid.

I synthesized 2-chloromethylthiophene from thiophene, concentrated hydrochloric acid, and formaldehyde.

by CognitiveFuel January 21, 2024

RC

An RC is a Research Chemical. Some research Chemicals get you high, or help you study at low doses (4F-MPH, a-PVP, Methcathinone). Some are milder and help you study with energy (Prolintane,

Methiopropamine, Ethiopropamine, Cathinone). Some research chemicals help you study (Phenylpiracetam Hydrazide, N-Acetyl-Selank, Selank, Semax). Some can cure depression permanently (NSI-189, 9-Me-BC). Some RCs can help you stay awake and remember stuff (Hydrafinil, Adrafinil, Fladrafinil, Flodafinil). Some RCs raise your mood by preventing breakdown of Dopamine and Norepinephrine (D,L-Deprenyl; Pheniprazine). Some are NDRIs (Thiopropamine, PhenylPropylAminoPentane). Some are histaminergic to help you wake up (Wakix, Sunosi, Modafini, Armodafinil, Flmodafinil, Fluorenol). Some RCs became medicine and can help with trauma to help you forget (Propranolol, Klonopin). Some are replacements for alcohol/ethanol (2-methyl-2-butanol, Bretazenyl). Some are empathogen-entatcogens (IndanylAminoPropane (IAP), IndanylMethylAminoPropane (IMAP)).

Warning /!\: The long term effects of research chemicals have not been studied.

Tony: I took 100mg of Flodafinil and stayed up for 12 hours straight. I was studying.

The next day, I took 30mg Ethiopropamine (EPA) and 100mg Phenylpiracetam Hydrazide and studied and cleaned my room for 6 hours. Thanks RC!

by CognitiveFuel September 11, 2023

Dibutyl ether

Dibutyl ether is an ether that is used for complex grignard reactions where higher temperatures are needed. Dibutyl ether is good for reacting benzyl magnesium chloride (made from benzyl chloride and magnesium turnings in dibutyl ether) with acetonitrile in dibutyl ether at elevated temperatures. Then reacting it with hydrochloric acid to get Phenyl-2-Propanone. Dibutyl ether increases the yield compared to diethyl ether. Dibutyl ether is produced by reacting butanol with sulfuric acid. The temperature cannot be too high, as butanol could dehydrate into butene (1-butene). The ether must be stored with butylated hydroxytoluene as explosive peroxides can form.
Properties
Chemical formula
C8H18O
Molar mass
130.231 g/mol
Appearance
Colorless liquid
Odor
Fruity
Density
0.77 g/cm3 (20 °C)
Melting point
−95 °C (−139 °F; 178 K)
Boiling point
141 °C (286 °F; 414 K)

I reacted benzyl magnesium chloride with acetonitrile in dibutyl ether and hydrolyzed it with hydrochloric acid to get Phenyl-2-Propanone.

by CognitiveFuel January 16, 2023

Khat

Khat is a plant with leaves that you chew to get energy and a high. It's relaxing yet stimulating. Khat leaves contain mostly cathine and a little cathinone and it's mostly the cathinone (phenylpropanoneamine, 2-aminopropiophenone) that gives you energy with cathine contributing very little to the energy and the high. Khat is used to study similar to Adderall, Ritalin, Modafinil, and Caffeine. Khat can be chewed freshly picked from the khat tree or brewed into a tea. The leaves must be used quickly, or it will all turn into cathine (phenylpropanolamine, D-Norpseudoephedrine) within 3 days of picking them. Khat is legal in some places like Ethiopia, Yemen, and South Africa, yet illegal in other places like the US and Canada. Khat releases dopamine and norepinephrine. Khat is like Caffeine, but stronger. Khat is Nature's Ritalin. The Khat plant needs less water than the Coffee plant and can withstand higher temperatures than the coffee plant. Khat loves the sunlight.

I picked and brewed fresh khat leaves. It gave me energy to study and do homework and clean. I got a nice high off of khat. Khat is the coffee of the future.

by CognitiveFuel January 8, 2023

Alaskan alarm clock

The Alaskan alarm clock is waking up your girlfriend or wife by throwing water with a ton of ice cubes or snow in it. Sometimes you can add live Alaskan Salmon. Then you both have some beers to warm up.

Tom: I woke up my wife with the Alaskan alarm clock. She complained she smelled like salmon and the beers didn't help. Now Stephanie made me sleep in the cold garage.

by CognitiveFuel September 2, 2023

Thiophene

Thiophene is a chemical that is useful in a lot of stuff. It can be bought or synthesized from butane and sulfer at the vapor phase at 65 °C. Thiophene is an aromatic compound. Thiophene can be chloromethylated by formaldehyde solution and hydrogen chloride at 5 °C or lower to 2-chloromethylthiophene/2-(Chloromethyl)thiophene (TP-MeCl).

Properties
Chemical formula
C4H4S
Molar mass
84.14 g/mol
Appearance
colorless liquid
Density
1.051 g/mL, liquid
Melting point
−38 °C (−36 °F; 235 K)
Boiling point
84 °C (183 °F; 357 K)
Magnetic susceptibility (χ)
-57.38·10−6 cm3/mol
Refractive index (nD)
1.5287
Viscosity
0.8712 cP at 0.2 °C
0.6432 cP at 22.4 °C

Tony: I synthesized 2-chloromethylthiophene from thiophene.

by CognitiveFuel September 11, 2023

White blood cells

White blood cells are cells inside of your body that kill of viruses, especially if if recognizes the virus. Vaccines are weakened or dead viruses that go into your body to help the white blood cells kill it so that if it encounters the alive form of the virus it could kill it easier. In addition, eating fruits and vegetables and especially onions can give the body and white blood cells vitamins and minerals and especially sulfer to help you kill off viruses and bacteria more. Also, kids get dirty and eat dirt and stuff that falls on the ground and that's OK (at least it used to be until coronavirus ruined it so we all got to wear masks and not eat stuff from the floor). Their white blood cells can fight it off and familiarize itself with bacteria and viruses. As long as they wash their hands afterwards and always after using the bathroom. Adults should also wash their hands when they use the bathroom. Some people died from the coronavirus. Some people got better, but they lost their sense of smell. White blood cells also help you fight off measles, mumps, rubella, meningitis, the flu, the common cold, chicken pox, and more. White blood cells are also in cartoon form in the movie, Osmosis Jones and the show Ozzy and Drix. The sky blue guy is Osmosis Jones (Ozzy, white blood cell) and the red and yellow guy is Drix (cold pill).

Tyler: I got a cold, but I'm drinking emergen-C and eating onion and avocado salad with lime and salt with rice and chicken. If it gets worse, I'll take a cold pill.

*gets worse
Tyler: Takes cold pill.
*white blood cell and cold pill attacking the common cold.
*4 days later

Tyler: Hey, my cold is all gone! Thanks white blood cells and cold pill.

by CognitiveFuel March 11, 2023