tweaker 

A 'speed'/'crystalmeth' freak.
Tweaker's are 'tripped out' addicts who live for 'gas'/'ice' and party for days with no concept of time or the outside world.

"Val Kilmer play's his best role ever as a hardcore tweaker, a crystalmeth freak, in a great movie called 'The Salton Sea'."

tweaker by Diego August 18, 2003

Tweaker 

A person who uses meth and staying awake for days at a time thinks their focused on there project usually something they think they can repair but in reallity they end up breaking it so the parts end up in a box with all the other tweaker parts

He has been up for days tweaking on electronic items , and hasnt fixed any of them , all he has now is a bunch of parts, he is such a tweaker.

Tweaker by Kimberly Delgado July 10, 2006

Tweaker 

Typically someone who smokes/snorts/does meth. Some people who have tweaker habits but don't do meth may also be referred to as a tweaker. People who are constantly touching their face, or looking around like they think someone is watching. A tweaker can typically be one of two kinds. Either very loud, weird, unusually happy about everything (or sometimes even angry) and is that "in your face" kind of person. Or that guy sitting at the back of the bus with his hood on staring at everyone nervously because he thinks they all know he's high.

A tweaker downtown today tried to sell me meth! Can you believe that?

Tweaker by LiaMiaLoshia December 12, 2014

tweaker 

someone who abuses methamphatamine.

usually skinny because they dont eat.
dark circles under their eyes because they dont sleep.
can harldy stand because most of their blood viens have collpased from constant injecting,

they transform themselves into a hermit-like state and keep to themselves while trying to have a normal life.

kid 1: i think that jon is using meth.
Kid2: yeah i definatly think he is a tweaker

tweaker by lovebabefor April 8, 2009

Tweaker 

Tweaker is tayisa, someone who's a hoe

Look at that hoe Tayisa, she's a tweaker

Tweaker by Angie08 May 9, 2017

tweaker 

1) A speed, or meth addict who has assumed the role of the drug, in other words, they lost their personality to the drug.
2) An ex- deadhead or hippie who has fried their brain and is now living in the small, paranoid world of warped memories of a mundane adolescence. They communicate by spreading urban legends as "amazing" inspirational stories that align with their perception of reality.
3) A stupid, spastic teen (or adult, but less common) that display ignorance and naivety with every action.

I was walking through the Haight the other day and was surrounded by tweakers.

I went to my high school reunion and the tweakers were still messed up in the head.

tweaker by stv October 5, 2004

Tweaker 

Mainly used in Philadelphia, A Tweaker is a female who gets around! A whore, smut, slut, hoe, or trick. "Tweak" can also be used in it's place, as well as "Tweaking"

Yo bul?

"Wassup with you bul?"

Shit!...whats up with Kaneisha and them?

"I don't know.....but I def heard her squad is some tweakers!"

Oh yea?.....they tweakin?

"That's What I Heard!"

Tweaker by mickey futuristic February 19, 2010